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Grape Seed Extract

Rejuvenation Therapeutics


  • Supports cardiovascular health.*
  • May help build muscle mass.*

Suitable for Vegans. Gluten Free. No artificial fillers, No Rice.

60 Vegan Capsules (1-Month Supply).


Suggested Use: Take 2 capsules once daily, or as directed by your qualified healthcare professional.

Warning: Consult a healthcare professional prior to use if you are pregnant or nursing, taking any medications, or have any medical conditions. Keep out of reach of children.

Store in a cool, dry place.

What is Grape Seed Extract?

Common Names: grape seed extract, grape seed

Latin Name: Vitis vinifera

Grape seed extract is an industrial derivative of whole grape seeds.

The extract contains proanthocyanidins.[1] In alternative medicine, grape seed extract is sold in dietary supplement form and claimed to have numerous health benefits.[1]

Since ancient Greece, people have used grapes, grape leaves, and sap for multiple health purposes, leading to the development of Grape seed extract in the 1970s.

Today, grape seed extract is used as a dietary supplement for various conditions, including for venous insufficiency (when veins have problems sending blood from the legs back to the heart), to promote wound healing, and to reduce inflammation.

What are the benefits of Grape Seed Extract?

Grape seed extract is composed of a complex mixture of flavonoids, Vitamin E, linoleic acid, and phenolic procyanidins.[3] These compounds can also be found in the skins and juices of the fruit. The active agents of extract are mostly polyphenols or OPCs (oligomeric procyanidins), which is usually the commercial reason why grape seeds are being extracted. Proanthocyanidins and catechins are the potent antioxidants in grape seeds that are believed to be 20 times greater than vitamin E and 50 times greater than vitamin C.[4]

Why take Grape Seed Extract?

Grape seed extract is used for conditions related to the heart and blood vessels, such as atherosclerosis (hardening of the arteries), high blood pressure, high cholesterol, and poor circulation.

Other reasons for the use of grape seed extract include complications related to diabetes, such as nerve and eye damage; vision problems, such as macular degeneration (which can cause blindness); and swelling after an injury or surgery.

Grape seed extract is also used for cancer prevention and wound healing.[5, 6]


  1. https://en.wikipedia.org/wiki/Grape_seed_extract
  2. “Grape Seed Extract, Herbs at a Glance”. US National Center for Complementary and Integrative Health, National Institutes of Health. September 2016.
  3. El-Beshbishy H, Mohamadin A, Abdel-Naim A. In Vitro Evaluation of the Antioxidant Activities of Grape Seed (Vitis vinifera) Extract, Blackseed (Nigella sativa) Extract and Curcumin. Journal of Taibah University Medical Sciences. 2009;4(1):23-35. doi:10.1016/s1658-3612(09)70078-2.
  4. Shi J, Yu J, Pohorly J, Kakuda Y. Polyphenolics in Grape Seeds—Biochemistry and Functionality. Journal of Medicinal Food. 2003;6(4):291-299. doi:10.1089/109662003772519831.
  5. Brooker S, Martin S, Pearson A, et al. Double-blind, placebo-controlled, randomised phase II trial of IH636 grape seed proanthocyanidin extract (GSPE) in patients with radiation-induced breast induration. Radiotherapy and Oncology.2006;79(1):45-51.
  6. Clouatre DL, Kandaswami C. Grape seed extract. In: Coates P, Blackman M, Cragg G, et al., eds. Encyclopedia of Dietary Supplements. New York, NY: Marcel Dekker; 2005:309-325.
  7. Grape. Natural Medicines Comprehensive Database Web site. Accessed at http://www.naturaldatabase.com on March 13, 2007.
  8. Grape seed (Vitis vinifera, Vitis coignetiae). Natural Standard Database Web site. Accessed at http://www.naturalstandard.com on March 13, 2007.
  9. http://www.wellnessproposals.com/health-care/complimentary-and-alternative-medicine/grapeseed-extract-factsheet.pdf

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.



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